Research only·Synthetic peptide (Thymosin Beta-4 fragment)
TB-500
aka Thymosin Beta-4 fragment
Education only. Many compounds discussed are research chemicals not approved for human use in the US. This is not medical advice — consult a licensed physician.
What it is
Synthetic version of the active region of thymosin beta-4. Studied alongside BPC-157 for soft tissue repair. No published human RCTs.
How it works
Animal studies suggest it promotes actin sequestration, cell migration, and angiogenesis — useful for wound healing and tissue regeneration.
What the research says
Animal studies show accelerated wound healing and cardiac repair. Used clinically in veterinary medicine. No human RCTs published.
Sources: PubMed: TB-500
Common dosing ranges
- Range
- 1–2 mg per dose (anecdotal protocols)
- Frequency
- Loading: 2× weekly for 4 weeks. Maintenance: 1× weekly for 4 weeks.
- Duration
- 8 weeks typical
Sources: PubMed reviews
Administration
SubQ · IM
Half-life
~2 hours
Side effects
Common
- Lethargy after injection
- Injection site reaction
Serious / theoretical
- Unknown long-term human safety; theoretical concern with active malignancy due to angiogenesis
Sources: PubMed
Notes
FDA placed TB-500 on the 503A "Category 2" bulks list in 2023.