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Research only·Synthetic peptide (gastric protein fragment)

BPC-157

aka Body Protection Compound 157, PL14736

Education only. Many compounds discussed are research chemicals not approved for human use in the US. This is not medical advice — consult a licensed physician.

What it is

A 15-amino-acid sequence derived from a protein in human gastric juice. Studied for tendon, ligament, and gut healing. No human RCTs published — all trial data is animal model.

How it works

Animal studies suggest it promotes angiogenesis (new blood vessel growth), modulates the nitric oxide system, and accelerates wound healing in tendon and gut tissue.

What the research says

Robust animal data on tendon repair, gut ulcer healing, and angiogenesis. Zero published human RCTs — all human use is anecdotal.

Sources: PubMed: BPC-157 reviews

Common dosing ranges

Range
Animal studies: 10 mcg/kg. Human protocols typically 250–500 mcg/day (no clinical validation).
Frequency
1–2× daily
Duration
Most protocols cycle 4–8 weeks on, then break

Sources: PubMed reviews

Administration

SubQ · Oral

Half-life

~30 minutes (parenteral)

Side effects

Common

  • Generally reported as well-tolerated in animal studies
  • Injection site irritation

Serious / theoretical

  • Unknown long-term human safety profile

Sources: PubMed

Notes

FDA placed BPC-157 on the 503A bulks list as "Category 2" (preliminary safety/efficacy concerns) in 2023.