Research only·Selective GHRP / ghrelin mimetic
Ipamorelin
Education only. Many compounds discussed are research chemicals not approved for human use in the US. This is not medical advice — consult a licensed physician.
What it is
Synthetic pentapeptide that selectively stimulates growth hormone release without significantly raising cortisol or prolactin (unlike older GHRPs).
How it works
Binds ghrelin receptor (GHSR-1a), triggering pituitary GH release. Selective compared to GHRP-2/GHRP-6.
What the research says
Phase 2 trials in postoperative ileus showed acceptable safety. No long-term outcome trials.
Sources: PubMed: Ipamorelin
Common dosing ranges
- Range
- 200–300 mcg per dose
- Frequency
- 1–3× daily, often before bed and post-workout
- Duration
- 8–12 week cycles
Sources: PubMed
Administration
SubQ
Half-life
~2 hours
Side effects
Common
- Hunger spike (ghrelin agonism)
- Mild headache
- Tingling
Serious / theoretical
- Unknown long-term GH effects
Sources: PubMed