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Research only·GHRH analog

CJC-1295

aka DAC-GRF, CJC-1295 with DAC

Education only. Many compounds discussed are research chemicals not approved for human use in the US. This is not medical advice — consult a licensed physician.

What it is

Synthetic GHRH analog. The DAC (drug affinity complex) version has an extended half-life (~8 days) compared to the no-DAC version (~30 min).

How it works

Binds GHRH receptors on the pituitary, stimulating endogenous GH pulses.

What the research says

Phase 1 PK study (Teichman 2006) confirmed GH/IGF-1 elevation. Long-term outcome trials lacking.

Sources: CJC-1295 PK study

Common dosing ranges

Range
No-DAC: 100 mcg with each Ipamorelin dose. DAC: 1–2 mg weekly.
Frequency
No-DAC: 1–3× daily. DAC: weekly.
Duration
8–12 week cycles

Sources: PubMed

Administration

SubQ

Half-life

No-DAC: ~30 min. DAC: ~8 days.

Side effects

Common

  • Injection site reaction
  • Flushing
  • Tingling

Serious / theoretical

  • Theoretical risks of chronic GH/IGF-1 elevation

Sources: PubMed